Therapeutic indications
In dogs, to be used against flea and/or tick infestations, when a repellent (anti-bite) activity against sandflies and/or mosquitoes is also necessary.
Fleas: for the treatment and prevention of flea infestations (ctenocephalides spp.). Fleas on dogs are killed within 24 hours of treatment. One treatment prevents infestation by new adult parasites for four weeks. The product can be used as part of a treatment strategy to control flea allergy dermatitis (FAD) when this has been previously diagnosed by your veterinary surgeon. Ticks: treatment of Diixodes ricinus tick infestations. One treatment determines, for four weeks, a persistent acaricidal efficacy against tick infestation (ixodes ricinus, dermacentor reticulatus and rhipicephalus sanguineus). If tick species (Dermacentor reticulatus and Rhipicephalus sanguineus) are present when the product is applied, not all are killed within 48 hours of treatment. Sandflies and mosquitoes: one treatment determines a repellent (anti-sting) activity against sandflies (phlebotomus perniciosus) and mosquitoes (culex pipiens, aedes aegypti) for four weeks.
Dosage and administration
Spot-on use.
Dosage: the minimum recommended dose is 6.7 mg fipronil/kg body weight and 60 mg permethrin/kg body weight
Dog weight: 1.5-4kg; fipronil (mg): 26.8; permethrin (mg): 240
Dog weight: 4-10kg; fipronil (mg): 67; permethrin (mg): 600
Dog weight: 10-20kg; fipronil (mg): 134; permethrin (mg): 1200
dog weight: 20-40 kg; fipronil (mg): 268; permethrin (mg): 2400
dog weight: 40-60 kg; fipronil (mg): 402; permethrin (mg): 3600
for dogs > 60 kg an appropriate combination of pipettes must be used.
Method of administration
remove the pipette from the blister. Hold the pipette upright. Shake the narrow part of the pipette to ensure that the contents are inside the main part of the pipette.
Break the seal on the top of the spot-on pipette along the marked line. Part the animal's fur until the skin is visible. Place the tip of the pipette directly against the exposed skin and gently squeeze several times to empty the contents into two to four different points, depending on body weight, on the animal's back.
As an indication for a dog weighing less than 20 kg the product must be applied in two points, while for dogs weighing more than 20 kg apply the product in 2-4 points. Treatment program: the use of the product must be based after confirmation of the infestation or risk of infestation, by fleas and/or ticks or when a repellent (anti-feeding) activity against sandflies and/or mosquitoes is also necessary. Depending on the degree of ectoparasitic infestation, the responsible veterinarian may recommend repeating the treatment. The interval between 2 treatments must not be less than 4 weeks.
Contraindications
Do not use in case of hypersensitivity to the active ingredients or to any of the excipients. Do not use on rabbits and cats where possible adverse reactions may occur up to and including death of the animal (refer to the "special precautions for use in animals" section). Do not use in sick animals (i.e. systemic diseases, fever) or in convalescent animals.
Excipients
Each pipette contains: fiprotix for very small breed dogs (toys): butylhydroxyanisole (e320) 0.088 mg; butylhydroxytoluene (e321) 0.044 mg fiprotix for small breed dogs: butylhydroxyanisole (e320) 0.22 mg; butylhydroxytoluene (e321) 0.11 mg fiprotix for medium dogs: butylhydroxyanisole (e320) 0.44 mg; butylhydroxytoluene (e321) 0.22 mg fiprotix for large breed dogs: butylhydroxyanisole (e320) 0.88 mg; butylhydroxytoluene (e321) 0.44 mg fiprotix for giant breed dogs: butylhydroxyanisole (e320) 1.32 mg; butylhydroxytoluene (e321) 0.66 mg.
Target species
Dog