Therapeutic indications
For the treatment and prevention of flea and tick infestations where repellent (anti-feeding) activity against sandflies, horse flies and mosquitoes is necessary. For the treatment and prevention of ctenocephalides felis flea infestations and the prevention of ctenocephalides canis flea infestations. The product eliminates fleas c. felis present on the animal within 24 hours.
One treatment prevents subsequent flea infestations for 4 weeks.
The product can be used as part of a strategic treatment for flea allergy dermatitis where it has been previously diagnosed by a veterinarian. The product has a repellent effect against ticks for 7 days and up to 4 weeks after treatment. However, individual ticks can attach themselves to the dog and come off within the first 24 hours of infestation. The product has an immediate acaricidal efficacy against rhipicephalus sanguineus and ixodes ricinus but it is possible that not all ticks will be eliminated within 48 hours of treatment if these are already present at the time of application of the product.
The frontline pesticide has an acaricidal efficacy against ticks that persists for 4 weeks. The product has a repellent (anti-feeding) efficacy for 3 weeks against sandflies and for 4 weeks against mosquitoes (culex pipiens). The product has a persistent insecticidal efficacy for 3 weeks against sandflies.
The drug repels and eliminates horse flies for five weeks.
Dosage and administration
For topical skin application (spot-on use).
The following table indicates the pipette to be used based on the dog's weight:
frontline tri-act spot-on solution for dogs: very small dogs 2-5kg; volume (ml): 0.5; fipronil (mg): 33.8; permethrin (mg): 252.4
frontline tri-act spot-on solution for dogs: small dogs 5-10 kg; volume (ml): 1; fipronil (mg): 67.6; permethrin (mg): 504.8
frontline tri-act spot-on solution for dogs: medium dogs 10-20 kg; volume (ml): 2; fipronil (mg): 135.2; permethrin (mg): 1009.6
frontline tri-act spot-on solution for dogs: large dogs 20-40 kg; volume (ml): 4; fipronil (mg): 270.4; permethrin (mg): 2019.2
frontline tri-act spot-on solution for dogs: very large dogs 40-60 kg; volume (ml): 6; fipronil (mg): 405.6; permethrin (mg): 3028.8
frontline tri-act spot-on solution for dogs: dogs > 60 kg: use the appropriate combination of the aforementioned pipettes for dogs weighing more than 60 kg, use the correct combination of two pipette sizes, which corresponds as closely as possible to the body weight of the dog.
Treatment program:
the use of the product must be based on the treatment of a confirmed infestation or on a risk of flea and/or tick infestation, where repellent activity is also necessary (anti-feeding) against sandflies and/or mosquitoes and/or horse flies. Repeating treatment may be indicated depending on exposure to ectoparasites.
In these cases, the interval between two consecutive treatments should be at least 4 weeks. Choose the right size pipette based on your dog's weight. For dogs weighing more than 60 kg, use the correct combination of two pipette sizes, which corresponds as closely as possible to the dog's body weight.
The product should be applied in two places out of the dog's licking range of the application site. These points are at the base of the head and at the base of the neck between the shoulder blades.
Contraindications
Do not use in sick or convalescent animals. Do not use in cats or rabbits, as potentially fatal adverse reactions may occur. Do not use in case of known hypersensitivity to the active ingredients or to one of the excipients.
Excipients
Frontline tri-act spot-on solution for dogs: very small dogs 2-5 kg; single dose volume (ml): 0.5; butylated hydroxytoluene (e321) (mg): 0.563 small dogs 5-10 kg; single dose volume (ml): 1; butylated hydroxytoluene (e321) (mg): 1.125 medium dogs 10-20 kg; single dose volume (ml): 2; butylated hydroxytoluene (e321) (mg): 2,250 large dogs 20-40 kg; single dose volume (ml): 4; butylated hydroxytoluene (e321) (mg): 4,500 approx
