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Zylkene 450 mg is a food supplement for medium-large dogs, specially developed for dogs between 15 and 60 kg in weight. This product is offered in packs of 100 capsules, thus offering a long-lasting supply ideal for extended cycles or continuous therapies. Zylkene is used to support animals during times of change or potentially stressful situations such as house moves, travel, new family members, fireworks, loud noises, vet visits, boarding or training. Thanks to its natural formula based on alpha-casozepine, derived from cow's milk proteins, Zylkene helps keep the dog calm in a safe way, without causing sedation and without compromising the animal's normal vitality or state of wakefulness.
Administration is very simple: the capsules can be administered whole or opened and mixed with normal foods, facilitating acceptance even in the most selective subjects regarding the intake of supplements. The effectiveness of Zylkene is supported by numerous studies conducted in collaboration with veterinary behaviourists, who recommend its use for effective and natural stress management. The product is free of artificial preservatives, colors and other potentially irritating substances, making it suitable even for dogs with food sensitivities. The palatability is excellent and many animals like the flavour, greatly simplifying administration both at home and outside.
This supplement stands out for its speed of action: generally, after a few regular administrations, an improvement in the dog's approach to stressful situations is already observed. It can be integrated into any type of diet (both commercial and homemade) and does not interfere with any ongoing pharmacological therapies, as long as it is agreed with your trusted veterinarian. It is also a valid support in broader behavioral rehabilitation plans or as temporary help in limited periods of greater emotional vulnerability for the dog.
Therapeutic Indications
Zylkene 450 mg is recommended for the management of stress and anxiety in medium and large breed dogs. The most common situations that may benefit from the use of this product include changes in the home environment, temporary removal of owners, long trips, placement in new families, stays in boarding houses or kennels, visits to the groomer or vet, as well as during vaccination campaigns or invasive medical treatments. It can also be administered in the presence of loud noises such as thunderstorms or fireworks, during social events involving large flows of people or animals, or in the event of the introduction of new animals into the home.
Zylkene is indicated as a non-pharmacological support in behavioral modification programs developed by veterinary behaviourists, promoting gradual adaptation to new or potentially anxiety-provoking situations. Counteracts the onset of typical manifestations of anxiety such as loss of appetite, excessive vocalizations, destructive behaviors, inappropriate elimination and hyperactivity. The relaxing action of alpha-casozepine helps the dog maintain a more balanced and manageable behavior both at home and during external activities.
The product can be used both as an acute intervention, for example for a few days before and during a planned stressful event (such as a move or a trip), and in continuous mode in subjects who show a constant predisposition to stress or mild forms of chronic anxiety. It is particularly suitable for dogs that have difficulty adapting to changes in routine or new social contexts, facilitating the return to the animal's general psychophysical well-being.
Composition
Active ingredient: Zylkene 450 mg contains alpha-casozepine, a patented molecule extracted from cow's milk casein through an enzymatic hydrolysis process. Alpha-casozepine works by binding to GABA receptors in the central nervous system, promoting relaxation without causing sedation or reduced alertness.
Each capsule, in addition to the active ingredient, contains excipients of natural origin carefully selected to guarantee maximum digestibility and safety, free of gluten, artificial preservatives or animal protein sources other than milk. Excipients include maltodextrins and magnesium stearate. The product does not contain common allergenic ingredients such as soy, wheat or added colors. Thanks to its pure and concentrated formulation, a single capsule per day is often sufficient to achieve satisfactory results in dogs of the corresponding weight range.
Zylkene does not alter the flavor of the foods with which it is mixed and, thanks to the delicate handling of the ingredients, reduces the risk of gastrointestinal side effects to a minimum. The formula is designed to be well tolerated even in dogs that follow specific diets or have food intolerances. All ingredients are of pharmaceutical quality and subjected to rigorous purity controls.
Contraindications
Zylkene 450 mg must not be administered to dogs with known hypersensitivity or allergy towards milk proteins or any of the other excipients present in the composition. Caution is advised in subjects who frequently develop adverse reactions to food supplements or who have chronic intestinal pathologies, in which the intake of powder could worsen the symptomatic picture. There are no known contraindications to concomitant use with most veterinary drugs, but it is still preferable to consult the veterinarian before starting administration, especially in subjects on chronic therapy or with complex pathological states.
In the absence of specific data, we do not recommend using the product on pregnant or breastfeeding bitches unless strictly necessary and under veterinary supervision. Do not use on puppies under three months of age, unless otherwise indicated by a veterinary surgeon. Pay particular attention if the dog shows clinical signs of intolerance, such as vomiting or persistent diarrhea after consumption: in these cases, immediately suspend the product and consult your trusted veterinarian to evaluate possible therapeutic alternatives.
Safety of the drug for the species
Zylkene 450 mg has been subjected to numerous safety studies which have demonstrated the absence of serious side effects even after prolonged administration in dogs of different sizes and body conditions. The choice to use exclusively ingredients of natural origin strongly limits the risk of toxicity or accumulation of unwelcome metabolites even during continuous use. In rare cases, some subjects may experience transient mild gastrointestinal disorders, which tend to resolve spontaneously by suspending or adapting the dosage.
Alpha-casozepine does not cause drowsiness or alteration of cognitive functions, so the dog can continue normal daily activities without compromise. In case of accidental overdose, clinical studies have confirmed that no particularly relevant adverse effects are to be expected, other than a possible increase in the production of soft stools which tends to resolve spontaneously by lowering the dosage. The supplement can also be used in elderly or debilitated animals under veterinary supervision, thus guaranteeing a wide margin of safety for all age groups.
Precautions
Before starting treatment with Zylkene 450 mg it is advisable to consult your veterinarian to identify the real cause of the behavioral discomfort and plan a stress management program suited to the specific needs of the dog. In subjects with a history of food allergies or specific intolerances, it is advisable to monitor the dog's reaction during the first administrations. Always store the product out of the reach of children and other pets, preferably in a cool, dry place.
Handling the capsules is simple, but it is advisable to wash your hands after each administration, especially if the capsules are opened and mixed with food. Never exceed the recommended dose in the absence of veterinary indications. If your dog shows signs of discomfort, stop administration immediately and contact your vet. The product should not be considered a substitute for a balanced diet or any pharmacological therapies that the dog may be following. It is important to remember that the behavioral/adjuvant aid must always be included in a re-education or behavioral modification process agreed with the specialist.
Method of administration
Zylkene 450 mg is administered orally, preferably once a day according to the recommended dosage depending on the dog's weight. The capsules can be opened and the contents mixed with the dog's favorite foods, to facilitate intake by the most wary subjects. It can be administered either on a full or empty stomach, according to individual tolerance, without risk of interference with digestion. In the case of particularly sensitive animals, it is possible to divide the daily dose into two administrations, morning and evening.
Not being a sedative drug, Zylkene can also be used during activities that require attention and physical activity, without causing the dog to break down. It is recommended to administer the product a few days before the start of potentially stressful events, to ensure that effective levels in the blood are achieved. The duration of the supplementation must be established based on the behavioral response of the animal and the indications of the veterinarian; in many cases we recommend administration for at least 10-15 days, prolonging the therapy if necessary without sudden interruptions.
Treatment program
Zylkene 450 mg can be used both for specific stress management needs and for longer-term support in cases of persistent or relapsing anxiety. The recommended dosage for each dog varies in relation to body weight: for animals between 15 and 30 kg one capsule per day is suggested, while for dogs between 30 and 60 kg the dose can be increased to two capsules per day, always divided according to veterinary indications. It is recommended to start administration at least 1-2 days before the stressful event in foreseeable cases, prolonging use throughout the entire period of exposure to anxiety-producing factors.
In cases of chronic stress or widespread anxiety, Zylkene can also be administered for periods of several weeks or months, subject to veterinary monitoring to evaluate the clinical progress and the need to continue, increase or suspend therapy. There are no known limitations to the overall duration of treatment if the dog tolerates the product well and effective behavioral improvement is observed. During the initial phase it is advisable to carefully monitor the dog's reactions to verify the individual response and adapt the dosage if necessary.
Target species
Dogs
